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The macula is the part of the retina near the back of the eye that is responsible for the clearest and sharpest images. Macular Degeneration refers to a progressive loss of vision caused by deterioration of the macula. There are several types of Macular Degeneration. Age-Related Macular Degeneration refers to the type associated with advanced age and is one of the leading causes of vision loss in the United States.